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Article

An ATP-dependent, Ran-independent mechanism for nuclear import of the U1A and U2B" spliceosome proteins.

The Journal of cell biology - 24 Jan 2000

Hetzer M, Mattaj I W

Abstract excerpt

Nuclear import of the two uracil-rich small nuclear ribonucleoprotein (U snRNP) components U1A and U2B" is mediated by unusually long and complex nuclear localization signals (NLSs). Here we investigate nuclear import of U1A and U2B" in vitro and demonstrate that it occurs by an active, saturable process. Several lines of evidence suggest that import of the two proteins occurs by an import mechanism different to...

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Source

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Identifiers

PMID: 10648562
DOI: 10.1083/jcb.148.2.293
PMCID: PMC2174293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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