Article
Prodynorphin allelic distribution in Scandinavian chronic alcoholics.
Alcoholism, clinical and experimental research - 1 Oct 1997
Geijer T, Jönsson E, Neiman J, Gyllander A, Sedvall G, Rydberg U, Terenius L
Abstract excerpt
Two regions of the human prodynorphin gene, the exon 4-region coding for the opioid peptides and the putative promotor/exon 1-region were analyzed for possible presence of polymorphisms. No polymorphism was detected in the exon 4-region, whereas a GC/AT base-pair exchange was observed 301 base pairs upstream of the exon 1/intron A boundary. This polymorphic marker was examined in Scandinavian chronic alcoholics...
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