Article
A genome-wide association study in 574 schizophrenia trios using DNA pooling.
Molecular psychiatry - 1 Aug 2009
Kirov G, Zaharieva I, Georgieva L, Moskvina V, Nikolov I, Cichon S, Hillmer A, Toncheva D, Owen M J, O'Donovan M C
Abstract excerpt
The cost of genome-wide association (GWA) studies can be prohibitively high when large samples are genotyped. We conducted a GWA study on schizophrenia (SZ) and to reduce the cost, we used DNA pooling. We used a parent-offspring trios design to avoid the potential problems of population stratific...
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