Article
Transcriptional control of the iron-responsive fxbA gene by the mycobacterial regulator IdeR.
Journal of bacteriology - 1 Jun 1999
Dussurget O, Timm J, Gomez M, Gold B, Yu S, Sabol S Z, Holmes R K, Jacobs W R, Smith I
Abstract excerpt
Exochelin is the primary extracellular siderophore of Mycobacterium smegmatis, and the iron-regulated fxbA gene encodes a putative formyltransferase, an essential enzyme in the exochelin biosynthetic pathway (E. H. Fiss, Y. Yu, and W. R. Jacobs, Jr., Mol. Microbiol. 14:557-569, 1994). We investigated the regulation of fxbA by the mycobacterial IdeR, a homolog of the Corynebacterium diphtheriae iron regulator DtxR...
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