Article
IdeR is required for iron homeostasis and virulence in Mycobacterium tuberculosis.
Molecular microbiology - 1 Jan 2014
Pandey Ruchi, Rodriguez G Marcela
Abstract excerpt
Iron is an essential but potentially harmful nutrient, poorly soluble in aerobic conditions, and not freely available in the human host. To acquire iron, bacteria have evolved high affinity iron acquisition systems that are expressed under iron limitation often in conjunction with virulence determinants. Because excess iron can be dangerous, intracellular iron must be tightly controlled. In mycobacteria, IdeR...
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