Article
An ideR mutant of Mycobacterium smegmatis has derepressed siderophore production and an altered oxidative-stress response.
Molecular microbiology - 1 Nov 1996
Dussurget O, Rodriguez M, Smith I
Abstract excerpt
The mycobacterial ideR protein is a homologue of the diphtheria-toxin repressor DtxR. We have previously demonstrated that Mycobacterium tuberculosis ideR, like DtxR, represses transcription of Corynebacterium diphtheriae iron-regulated promoters in vivo and binds to C. diphtheriae operators in a metal-dependent manner in vitro. We show here that ideR mutants of M. smegmatis, constructed by allelic replacement,...
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