A conserved sequence in histone H2A which is a ubiquitination site in higher eucaryotes is not required for growth in Saccharomyces cerevisiae.

doi:10.1128/mcb.10.9.4905-4911.1990

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Article

A conserved sequence in histone H2A which is a ubiquitination site in higher eucaryotes is not required for growth in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Sept 1990

Swerdlow P S, Schuster T, Finley D

Abstract excerpt

Histones H2A and H2B are modified by ubiquitination of specific lysine residues in higher and lower eucaryotes. To identify functions of ubiquitinated histone H2A, we studied an organism in which genetic analysis of histones is feasible, the yeast Saccharomyces cerevisiae. Surprisingly, immunoblo...

Topics

Base Sequence
Eukaryotic Cells
Genotype
Histones
Molecular Sequence Data
Mutation
Oligonucleotide Probes
Phenotype
Plasmids
Saccharomyces cerevisiae
Species Specificity

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