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Article

The engagement of Sec61p in the ER dislocation process.

Molecular cell - 1 Dec 1999

Zhou M, Schekman R

Abstract excerpt

Sec61p comprises the endoplasmic reticulum (ER) channel through which nascent polypeptides are imported and from which malfolded proteins have been suggested to be exported, or dislocated, back to the cytoplasm. We have devised a genetic screen for dislocation-specific mutant alleles of SEC61 from S. cerevisiae by employing the unfolded protein response to report on the accumulation of misfolded proteins in the...

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Identifiers

PMID: 10635318
DOI: 10.1016/s1097-2765(00)80222-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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