Article
The ephrins and Eph receptors in angiogenesis.
Cytokine & growth factor reviews - 1 Feb 2002
Cheng Nikki, Brantley Dana M, Chen Jin
Abstract excerpt
Eph receptors are a unique family of receptor tyrosine kinases that play critical roles in embryonic patterning, neuronal targeting, vascular development and adult neovascularization. Engagement of Eph receptors by ephrin ligands mediates critical steps of angiogenesis, including juxtacrine cell-cell contacts, cell adhesion to extracellular matrix, and cell migration. Recent evidence from in vitro angiogenesis...
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