Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of the HIV-1 nef gene in five intravenous drug users with long-term nonprogressive HIV-1 infection in Italy.

Journal of medical virology - 1 Mar 2000

Catucci M, Venturi G, Romano L, Valensin P E, Zazzi M

Abstract excerpt

Great variability in the course of human immunodeficiency virus type 1 (HIV-1) infection results from a complex interplay between host and virus factors. Some of the patients with prolonged nonprogressive infection have been reported to harbor virus variants with gross deletions in the accessory nef gene that has been implicated in in vivo pathogenicity in simian and mouse models. To investigate the role of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Viral
Share to Genes, nef
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to HIV Long-Term Survivors

Share to Sequence Homology, Amino Acid

Share to Substance Abuse, Intravenous

Source

Identifiers

PMID: 10630962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of the HIV-1 nef gene in five intravenous drug users with long-term nonprogressive HIV-1 infection in Italy.PMID 10630962Read ↗

HIV-1 nef mutations and clinical long-term nonprogression. A molecular epidemiology study.Semantic proximity Read ↗

Defective nef alleles in a cohort of hemophiliacs with progressing and nonprogressing HIV-1 infection.Semantic proximity Read ↗

Sequence variations in human immunodeficiency virus type 1 Nef are associated with different stages of disease.Semantic proximity Read ↗

Grossly DefectivenefGene Sequences in a Human Immunodeficiency Virus Type 1-Seropositive Long-Term NonprogressorSemantic proximity Read ↗

Nef alleles from human immunodeficiency virus type 1-infected long-term-nonprogressor hemophiliacs with or without late disease progression are defective in enhancing virus replication and CD4 down-regulation.Semantic proximity Read ↗

Genetic and functional analysis of HIV type 1 nef gene derived from long-term nonprogressor children: association of attenuated variants with slow progression to pediatric AIDS.Semantic proximity Read ↗

Structural defects and variations in the HIV-1 nef gene from rapid, slow and non-progressor children.Semantic proximity Read ↗

Partial "repair" of defective NEF genes in a long-term nonprogressor with human immunodeficiency virus type 1 infection.Semantic proximity Read ↗

High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection.Semantic proximity Read ↗

Sequence heterogeneity in human immunodeficiency virus type 1 nef in patients presenting with rapid progression and delayed progression to AIDS.Semantic proximity Read ↗

Natural variation of the nef gene in human immunodeficiency virus type 2 infections in Portugal.Semantic proximity Read ↗

Functional and structural defects in HIV type 1 nef genes derived from pediatric long-term survivors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.