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Article

High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection.

Journal of virology - 1 Nov 1996

Mariani R, Kirchhoff F, Greenough T C, Sullivan J L, Desrosiers R C, Skowronski J

Abstract excerpt

A large number of nef alleles were obtained from peripheral blood mononuclear cells (PBMC) of four long-term nonprogressing survivors of human immunodeficiency virus type 1 (HIV-1) infection and from five individuals with progressive HIV-1 infection. These primary nef alleles were characterized by DNA sequence analysis and for their ability to downregulate CD4 surface expression. Intact nef open reading frames...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 8892896
DOI: 10.1128/JVI.70.11.7752-7764.1996
PMCID: PMC190845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection.PMID 8892896Read ↗

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