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<i>Cytochrome P450</i> gene expression levels in peripheral blood mononuclear cells in comparison with the liver

1 Jun 2004

Abstract excerpt

Cytochromes p450 (CYPs) compose a superfamily of similar proteins involved in detoxification and elimination, as well as activation of a wide variety of compounds. Most CYP family members are localized in the liver. In order to assess whether peripheral blood leukocytes (PBL) are available as a surrogate for the determination of CYP gene expression levels in the liver, we compared CYP gene expression levels in...

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PMID: 15182434
DOI: 10.1111/j.1349-7006.2004.tb03243.x

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