Helicobacter pylori strain-specific genotypes and modulation of the gastric epithelial cell cycle.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Helicobacter pylori strain-specific genotypes and modulation of the gastric epithelial cell cycle.

Cancer research - 15 Dec 1999

Peek R M, Blaser M J, Mays D J, Forsyth M H, Cover T L, Song S Y, Krishna U, Pietenpol J A

Abstract excerpt

Helicobacter pylori cag+ strains enhance gastric epithelial cell proliferation and attenuate apoptosis in vivo, which may partially explain the increased risk of gastric cancer associated with these strains. The goals of this study were to identify specific H. pylori genes that regulate epithelial cell cycle events and determine whether these effects were dependent upon p53-mediated pathways. AGS gastric...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle
Share to Cell Survival
Share to Cyclin-Dependent Kinase Inhibitor p21
Share to Cyclins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastric Mucosa

Share to Helicobacter Infections

Share to Helicobacter pylori

Share to Proto-Oncogene Proteins c-mdm2

Source

Open in PubMed

Identifiers

PMID: 10626802

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.