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Article

Comparative genomic study of gastric epithelial cells co-cultured with Helicobacter pylori.

World journal of gastroenterology - 28 Dec 2012

Wang Fen, Luo Li-Dan, Pan Jian-Hua, Huang Li-Hua, Lv Hong-Wei, Guo Qin, Xu Can-Xia, Shen Shou-Rong

Abstract excerpt

AIM: To identify genes potentially involved in Helicobacter pylori (H. pylori)-induced gastric carcinogenesis. METHODS: GES-1 cells were co-cultured with H. pylori strains isolated from patients with gastric carcinoma (GC, n = 10) or chronic gastritis (CG, n = 10) for in vitro proliferation and apoptosis assays to identify the most and least virulent strains. These two strains were cagA-genotyped and used for...

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Identifiers

PMID: 23326126
DOI: 10.3748/wjg.v18.i48.7212
PMCID: PMC3544023

Genes

HDAC6
TRAF1
BRCA1
JUN
KRAS
SMAD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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