Article
Helicobacter pylori alters gastric epithelial cell cycle events and gastrin secretion in Mongolian gerbils.
Gastroenterology - 1 Jan 2000
Peek R M, Wirth H P, Moss S F, Yang M, Abdalla A M, Tham K T, Zhang T, Tang L H, Modlin I M, Blaser M J
Abstract excerpt
BACKGROUND & AIMS: Human colonization with Helicobacter pylori increases the risk for distal gastric adenocarcinoma, possibly by altering gastric epithelial cell cycle events and/or gastrin secretion. This study aimed to determine whether H. pylori virulence-related characteristics affect apoptosis, proliferation, and gastrin levels in a rodent model of gastric adenocarcinoma. METHODS: Mongolian gerbils were...
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