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Article

Epithelial intestinal cell apoptosis induced by Helicobacter pylori depends on expression of the cag pathogenicity island phenotype.

Infection and immunity - 1 Aug 2001

Le'Negrate G, Ricci V, Hofman V, Mograbi B, Hofman P, Rossi B

Abstract excerpt

Helicobacter pylori has been shown to induce chronic active gastritis and peptic ulcer and may contribute to the development of duodenal ulcer. Previous studies have shown that H. pylori mediates apoptosis of gastric epithelial cells via a Fas-dependent pathway. However, evidence for the induction of such a mechanism in intestinal epithelial cells (IEC) by H. pylori infection has not been demonstrated yet. This...

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Identifiers

PMID: 11447179
DOI: 10.1128/IAI.69.8.5001-5009.2001
PMCID: PMC98593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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