Article
Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin.
Cancer research - 1 Mar 2003
Cover Timothy L, Krishna Uma S, Israel Dawn A, Peek Richard M
Abstract excerpt
Chronic gastritis induced by Helicobacter pylori is a strong risk factor for the development of distal gastric adenocarcinoma. A specific host response to H. pylori that may contribute to gastric carcinogenesis is epithelial cell apoptosis. The aim of this study was to investigate the capacity of H. pylori vacuolating toxin (VacA) to induce gastric epithelial cell apoptosis. When cocultured with AGS gastric...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
