Article
Helicobacter pylori cagA+ strains and dissociation of gastric epithelial cell proliferation from apoptosis.
Journal of the National Cancer Institute - 18 Jun 1997
Peek R M, Moss S F, Tham K T, Pérez-Pérez G I, Wang S, Miller G G, Atherton J C, Holt P R, Blaser M J
Abstract excerpt
BACKGROUND: Infection with Helicobacter pylori induces chronic gastritis in virtually all infected persons, and such gastritis has been associated with an increased risk of developing gastric cancer. This risk is further enhanced with cagA+ (positive for cytotoxin-associated gene A) H. pylori strains and may be a consequence of induced gastric cell proliferation and/or alteration in apoptosis (programmed cell...
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