Article
Lack of association between alpha1-antichymotrypsin polymorphism and late-onset depressive disorder.
Psychiatry research - 29 Nov 1999
Ohara K, Suzuki Y, Yoshida K, Terada H, Ohara K
Abstract excerpt
Late-onset depressive disorder (LOD) has been thought to be associated with dementia. Recently, it was reported that the position-15 (alanine) polymorphism of the alpha1-antichymotrypsin gene (ACT*A) was a risk factor for Alzheimer's disease. We wondered whether the ACT*A allele frequency might be elevated in LOD. ACT genotyping was performed as described by Kamboh et al. (Kamboh, M.I., Sanghera D.K., Ferrell...
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