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Article

The APOE epsilon 4 polymorphism does not predict late onset depression: the Three-City Study.

Neurobiology of aging - 1 Apr 2016

Tully Phillip J, Péres Karine, Berr Claudine, Tzourio Christophe

Abstract excerpt

The apolipoprotein E ε4 allele (APOE4) is an established risk factor for dementia; however, conflicting findings have been reported as to whether this phenotype confers a heightened risk for late onset depression (LOD) independent of dementia. We examined 2242 persons for incident LOD who also underwent genotyping for APOE4. Major LOD was associated with female sex (odds ratio, 3.61; 95% confidence interval,...

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Source

Identifiers

PMID: 26785975
DOI: 10.1016/j.neurobiolaging.2015.12.018

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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