Article
No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset Alzheimer disease patients.
Neuroscience letters - 3 Jul 1998
Bass M P, Yamaoka L H, Scott W K, Gaskell P C, Welsh-Bohmer K A, Roses A D, Saunders A M, Haines J L, Pericak-Vance M A
Abstract excerpt
The alpha1-antichymotrypsin (AACT)-155 allele was found elsewhere to have a significant effect on Alzheimer disease (AD) risk in individuals with at least one APOE-4 allele. We compared AACT genotypes of 284 cases of sporadic AD and 172 controls. The frequency of the AACT-155 allele did not diffe...
Topics
- Adult
- Age of Onset
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Polymorphism, Genetic
- Risk Factors
- alpha 1-Antichymotrypsin