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Article

Alpha-1-antichymotrypsin polymorphism in schizophrenia: frequency, age at onset and cognitive function.

Neuropsychobiology - 1 Jan 1999

Chiu H J, Hong C J, Chen J Y, Wang Y C, Lin C Y, Bai Y M, Song H L, Lai H C, Tsai S J

Abstract excerpt

A common polymorphism in the alpha1-antichymotrypsin (ACT) gene is associated with Alzheimer's disease. ACT is also a trophic factor in the hippocampal neurons. In order to examine if the ACT gene plays a role in the pathogenesis of schizophrenic disorders, patients (n = 175) and control subjects (n = 114) were genotyped for ACT. We also investigated the relationship between genotypes and patients' cognitive...

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Source

Identifiers

PMID: 10474060
DOI: 10.1159/000026600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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