Article
Absence of association of alpha1-antichymotrypsin polymorphisms with Alzheimer's disease: a report on autopsy-confirmed cases.
Experimental neurology - 1 Jun 1998
Itabashi S, Arai H, Matsui T, Matsushita S, Muramatsu T, Higuchi S, Trojanowski J Q, Sasaki H
Abstract excerpt
alpha1-Antichymotrypsin (ACT) polymorphisms were examined in 79 cases with autopsy-confirmed Alzheimer's disease (AD) as well as in 28 cases with autopsy-confirmed nonneurological diseases to test the hypothesis that ACT polymorphisms confer a risk to an individual to develop AD. Neither ACT genotype frequency nor ACT allele frequency in the AD group was significantly different from the control group. The ACT...
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