Article
Kinetic measurements of binding of galectin 3 to a laminin substratum.
Glycoconjugate journal - 1 Jul 1999
Barboni E A, Bawumia S, Hughes R C
Abstract excerpt
Galectin 3, a beta-galactoside binding protein, contains a C-terminal carbohydrate recognition domain (CRD) and an N-terminal segment including multiple repeats of a proline/tyrosine/glycine-rich motif. Previous work has shown that galectin 3 but not the isolated CRD binds to laminin, a multivalent ligand, with positive cooperativety indicating the formation of multiple interactions although the lectin in...
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