Article
Peptides specific to the galectin-3 carbohydrate recognition domain inhibit metastasis-associated cancer cell adhesion.
Carcinogenesis - 1 Feb 2005
Zou Jun, Glinsky Vladislav V, Landon Linda A, Matthews Leslie, Deutscher Susan L
Abstract excerpt
Intravascular cancer cell adhesion plays a significant role in the metastatic process. Studies indicate that galectin-3, a member of the galectin family of soluble animal lectins, is involved in carbohydrate-mediated metastatic cell heterotypic (between carcinoma cells and endothelium) and homoty...
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