Article
Label-free characterization of cell adhesion using reflectometric interference spectroscopy (RIfS).
Analytical and bioanalytical chemistry - 1 Jan 2006
Möhrle Bernd P, Köhler Karsten, Jaehrling Jan, Brock Roland, Gauglitz Günter
Abstract excerpt
Reflectometric interference spectroscopy (RIfS) is a label-free, time-resolved technique for detecting interactions of molecules immobilized on a surface with ligands in solution. Here we show that RIfS also permits the detection of the adhesion of tissue culture cells to a functionalized surface in a flow system. Interactions of T cells with other leukocytes or epithelial cells of blood vessels are crucial steps...
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