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Article

Kinetic analysis of L1 homophilic interaction: role of the first four immunoglobulin domains and implications on binding mechanism.

The Journal of biological chemistry - 17 Oct 2008

Gouveia Ricardo M, Gomes Cláudio M, Sousa Marcos, Alves Paula M, Costa Júlia

Abstract excerpt

L1 is a cell adhesion molecule of the immunoglobulin (Ig) superfamily, critical for central nervous system development, and involved in several neuronal biological events. It is a type I membrane glycoprotein. The L1 ectodomain, composed of six Ig-like and five fibronectin (Fn) type-III domains, is involved in homophilic binding. Here, co-immunoprecipitation studies between recombinant truncated forms of human L1...

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Identifiers

PMID: 18701456
DOI: 10.1074/jbc.M804991200
PMCID: PMC2661381

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ECD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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