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Article

Stepped changes of monovalent ligand-binding force during ligand-induced clustering of integrin alphaIIB beta3.

The Journal of biological chemistry - 1 Sept 2006

Hsieh Chia-Fen, Chang Bo-Jui, Pai Chyi-Huey, Chen Hsuan-Yi, Tsai Jin-Wu, Yi Yung-Hsiang, Chiang Yi-Ting, Wang Da-Wei, Chi Sien, Hsu Long, Lin Chi-Hung

Abstract excerpt

Recent evidence demonstrated that conformational changes of the integrin during receptor activation affected its binding to extracellular matrix; however, experimental assessment of ligand-receptor binding following the initial molecular interaction has rarely been carried out at a single-molecul...

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Identifiers

PMID: 16793773
DOI: 10.1074/jbc.M601793200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16793773-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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