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Article

Expression and regulation of a molecular marker, SPR1, in multistep bronchial carcinogenesis.

American journal of respiratory cell and molecular biology - 1 Jan 2000

Lau D, Xue L, Hu R, Liaw T, Wu R, Reddy S

Abstract excerpt

A small proline-rich protein, SPR1, is overexpressed in squamous metaplasia of bronchial epithelium. We studied the expression and regulation of SPR1 in a series of human bronchial epithelial cell lines representing a model of multistep bronchial carcinogenesis. These cell lines included a primary culture of tracheobronchial epithelial cells (HTBE), a papilloma virus-transformed tracheobronchial epithelial cell...

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Source

Identifiers

PMID: 10615070
DOI: 10.1165/ajrcmb.22.1.3637

Genes

HBE1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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