Article
Establishment and characterization of a SV40T-transformed human bronchial epithelial cell line.
Lung cancer (Amsterdam, Netherlands) - 1 Jan 1998
Lu Y J, Guo S P, Tong T, Xu L H, Dong X Y, Hana N J, Cheng S J
Abstract excerpt
The majority of human lung cancers originate from the carcinogenesis of bronchial epithelial cells. To study the malignant progression of human bronchial epithelial cells, we established a SV40T-transformed human bronchial epithelial cell line, and observed some biological and genetic changes of the cell line at different passages. In a 2-year culture, this cell line was approaching malignancy without obvious...
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