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Article

Nuclear Receptor Expression and Function in Human Lung Cancer Pathogenesis.

PloS one - 1 Jan 2015

Kim Jihye, Sato Mitsuo, Choi Jong-Whan, Kim Hyun-Won, Yeh Byung-Il, Larsen Jill E, Minna John D, Cha Jeong-Heon, Jeong Yangsik

Abstract excerpt

Lung cancer is caused by combinations of diverse genetic mutations. Here, to understand the relevance of nuclear receptors (NRs) in the oncogene-associated lung cancer pathogenesis, we investigated the expression profile of the entire 48 NR members by using QPCR analysis in a panel of human bronchial epithelial cells (HBECs) that included precancerous and tumorigenic HBECs harboring oncogenic K-rasV12 and/or p53...

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Identifiers

PMID: 26244663
DOI: 10.1371/journal.pone.0134842
PMCID: PMC4526668

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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