Article
Hemiplegic mutations in AraC protein.
Journal of molecular biology - 26 Nov 1999
Reed W L, Schleif R F
Abstract excerpt
We have isolated mutations in AraC protein that specifically block either induction or repression at the ara pBAD promoter. These hemiplegic mutations identify amino acid residues that, correspondingly, are involved only in the induction or only in the repression activities of the protein. Residues key only for induction are 13, 15, and 18, which are located in the N-terminal arm of AraC, and residues 80 and 82...
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