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Article

Mapping arm-DNA-binding domain interactions in AraC.

Journal of molecular biology - 6 Apr 2001

Wu M, Schleif R

Abstract excerpt

AraC protein, the regulator of the l-arabinose operon in Escherichia coli has been postulated to function by a light switch mechanism. According to this mechanism, it should be possible to find mutations in the DNA-binding domain of AraC that result in weaker arm-DNA-binding domain interactions and which make the protein constitutive, that is, it no longer requires arabinose to activate transcription. We isolated...

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Identifiers

PMID: 11286551
DOI: 10.1006/jmbi.2001.4531

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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