Article
Strengthened arm-dimerization domain interactions in AraC.
The Journal of biological chemistry - 26 Jan 2001
Wu M, Schleif R
Abstract excerpt
Constitutive mutations were sought and found in the N-terminal arm of the Escherichia coli regulatory protein of the arabinose operon, AraC protein. A new mutation, N16D, was of particular interest. Asn-16 is not seen in the crystal structure of the AraC dimerization domain determined in the absence of arabinose, because the N-terminal arm 18 residues are disordered, but in the presence of arabinose, residues...
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