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Article

Frequent occurrence of loss of heterozygosity among tumor suppressor genes in uterine leiomyosarcoma.

Gynecologic oncology - 1 Dec 1999

Zhai Y L, Nikaido T, Orii A, Horiuchi A, Toki T, Fujii S

Abstract excerpt

OBJECTIVE: Leiomyosarcoma of the uterus is a rare smooth muscle tumor; it is extremely malignant and the rates of local recurrence and metastasis are high. Since tumor suppressor genes are commonly altered in malignant tumors, it is possible that mutations in such genes are involved in the development of uterine leiomyosarcoma. METHODS: Fifty-five patients (37-70 years of age) diagnosed as having smooth muscle...

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PMID: 10600306
DOI: 10.1006/gyno.1999.5629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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