Article
Stratification techniques to explore genotype environment interactions.
Genetic epidemiology - 1 Jan 1999
Wilk J B, Premkumar S, Nicolaou M, Myers R H, Maher N E, Harmon M D, Farrer L A, DeStefano A L, Cupples L A, Couropmitree N N
Abstract excerpt
Linkage analysis was performed on the GAW11 Problem 2 data set using stratification to explore the effects of the environmental risk factors and the differences between mild and severe phenotypes. Analysis of the four study populations stratified by the two risk factors identified regions on chromosomes 3 and 5 with significant evidence for linkage. Other loci were sought by removing families consistent with...
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