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Investigation of a candidate gene, environment, and G x E interaction using case-control and case-parent study designs.

Genetic epidemiology - 1 Jan 2001

Norris J M, Selinger-Leneman H, Génin E

Abstract excerpt

We investigated the independent contributions of a candidate gene and an environmental factor, and the presence of gene x environment (G x E) interaction, in the etiology of a disease in the Genetic Analysis Workshop (GAW) 12 problem 2 simulated data using a two-stage approach utilizing both case-control and case-parent study designs. Using the case-control design, several SNPs within candidate gene 1 (CG1) and...

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Identifiers

PMID: 11793790
DOI: 10.1002/gepi.2001.21.s1.s843

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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