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Article

A general test for gene-environment interaction in sib pair-based association analysis of quantitative traits.

Behavior genetics - 1 Jul 2008

van der Sluis Sophie, Dolan Conor V, Neale Michael C, Posthuma Danielle

Abstract excerpt

Several association studies support the hypothesis that genetic variants can modify the influence of environmental factors on behavioral outcomes, i.e., G x E interaction. The case-control design used in these studies is powerful, but population stratification with respect to allele frequencies can give rise to false positive or false negative associations. Stratification with respect to the environmental factors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18389355
DOI: 10.1007/s10519-008-9201-8
PMCID: PMC2480607

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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