Article
Covariates in linkage analysis.
Genetic epidemiology - 1 Jan 1999
Rice J P, Rochberg N, Neuman R J, Saccone N L, Liu K Y, Zhang X, Culverhouse R
Abstract excerpt
We apply a novel technique to detect significant covariates in linkage analysis using a logistic regression approach. An overall test of linkage is first performed to determine whether there is significant perturbation from the expected 50% sharing under the hypothesis of no linkage; if the overall test is significant, the importance of the individual covariate is assessed. In addition, association analyses were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.