Article
Avoiding false discoveries in association studies.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007
Sabatti Chiara
Abstract excerpt
We consider the problem of controlling false discoveries in association studies. We assume that the design of the study is adequate so that the "false discoveries" are potentially only because of random chance, not to confounding or other flaws. Under this premise, we review the statistical framework for hypothesis testing and correction for multiple comparisons. We consider in detail the currently accepted...
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