Article
Covariates in linkage analysis using sibling and cousin pairs.
Genetic epidemiology - 1 Jan 2001
Saccone N L, Rochberg N, Neuman R J, Rice J P
Abstract excerpt
Using simulated data from GAW 12, problem 2, we further develop a novel technique to detect and use significant covariates in linkage analysis. The method, first introduced by Rice et al. [Genet Epidemiol 17(Suppl. 1):S691-5, 1999], uses logistic regression to model perturbation in sharing as a function of covariate levels. The original method allows use of all sib pairs (concordant affected, concordant...
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