Article
Detection and modeling of disease susceptibility locus effects: how much can be learned from contrast of populations?
Genetic epidemiology - 1 Jan 1999
Génin E, Guyon F, Margaritte-Jeannin P, Quesneville H, Clerget-Darpoux F
Abstract excerpt
We report the results of our analyses of the GAW11 Problem 2 data set, using information from three different populations. In the first part of the paper, we used classical population genetic tests to compare affected individuals from the different populations, stratifying on the environmental factors. Thanks to existing linkage disequilibrium in one population, we found one of the disease susceptibility loci. In...
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