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Article

On the identification of disease mutations by the analysis of haplotype similarity and goodness of fit.

American journal of human genetics - 1 Apr 2003

Tzeng Jung-Ying, Devlin B, Wasserman Larry, Roeder Kathryn

Abstract excerpt

The observation that haplotypes from a particular region of the genome differ between affected and unaffected individuals or between chromosomes transmitted to affected individuals versus those not transmitted is sound evidence for a disease-liability mutation in the region. Tests for differentiation of haplotype distributions often take the form of either Pearson's chi(2) statistic or tests based on the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12610778
DOI: 10.1086/373881
PMCID: PMC1180352

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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