Article
Using case-control designs for genome-wide screening for associations between genetic markers and disease susceptibility loci.
Genetic epidemiology - 1 Jan 1999
Yang Q, Khoury M J, Atkinson M, Sun F, Cheng R, Flanders W D
Abstract excerpt
We used a case-control design to scan the genome for any associations between genetic markers and disease susceptibility loci using the first two replicates of the Mycenaean population from the GAW11 (Problem 2) data. Using a case-control approach, we constructed a series of 2-by-3 tables for each allele of every marker on all six chromosomes. Odds ratios (ORs) and 95% confidence intervals (95% CI) were estimated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.