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Article

Combined linkage and linkage disequilibrium mapping for genome screens.

Genetic epidemiology - 1 Oct 2000

Xiong M, Jin L

Abstract excerpt

Linkage analysis and association studies, two major approaches for genetic studies of human diseases, are useful for mapping genes that are highly penetrant, but both use only part of the information that is available for mapping disease genes. Therefore, they provide limited utility when used alone. In this report, we present combined linkage and linkage disequilibrium mapping that simultaneously utilizes...

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PMID: 11015125
DOI: 10.1002/1098-2272(200010)19:3<211::AID-GEPI3>3.0.CO;2-L

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