Article
In vivo regulation of von willebrand factor synthesis: von Willebrand factor production in endothelial cells after lung transplantation between normal pigs and von Willebrand factor-deficient pigs.
Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 1999
Brouland J P, Egan T, Roussi J, Bonneau M, Pignaud G, Bal C, Vaiman M, André P, Hervé P, Mazmanian G M, Drouet L
Abstract excerpt
To evaluate the regulation of plasma von Willebrand factor (vWF) and its in situ production by endothelial cells (ECs), 12 swine leukocyte antigen (SLA)-compatible left lung transplantations were performed. Normal lungs were transplanted into 10 pigs homozygous for von Willebrand disease and into 2 normal pigs. Additionally, 1 normal pig underwent pneumonectomy, and 1 SLA-incompatible lung transplantation between...
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