Article
The role of donor versus recipient tissue factor in coagulopathy during pig-to-primate xenotransplantation
2010-01-01
Abstract excerpt
The increasing demand for organs has stimulated the necessity in xenotransplantion, which promises an unlimited supply of organs for clinical use. However, coagulopathy of xenografts remains a major hurdle to successful pig-to-primate xenotransplantation. The ability to generate pigs expressing a human complement-regulatory protein (hCRP) and/or pigs in which the α1,3-Galactosyltransferase gene has been knocked-ou...
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Identifiers and source
- Literature Corpus work
- 916c7943-29f7-5b08-a70c-9c02261e8d23
- DOI
- 10.25560/5620