Article
Kidney xenotransplantation.
Kidney international - 1 Feb 2014
Cowan Peter J, Cooper David K C, d'Apice Anthony J F
Abstract excerpt
Xenotransplantation using pigs as donors offers the possibility of eliminating the chronic shortage of donor kidneys, but there are several obstacles to be overcome before this goal can be achieved. Preclinical studies have shown that, while porcine renal xenografts are broadly compatible physiologically, they provoke a complex rejection process involving preformed and elicited antibodies, heightened innate...
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