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Article

Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 and IgM anti-Gal antibodies.

Xenotransplantation - 1 Sept 2002

Saethre Marit, Sølvik Una Ø, Haraldsen Guttorm, Fiane Arnt E, Boretti Eva, Thorsby Erik, Platt Jeffrey L, Mollnes Tom E

Abstract excerpt

Naturally occurring anti-Galalpha1-3Gal (anti-Gal) antibodies and complement induce hyperacute rejection (HAR) of porcine organs transplanted to primates. If the hyperacute reaction is prevented, an acute vascular rejection (AVR) occurs within hours to few days. Antibodies are important for the development of AVR, whereas the role of complement is still not clarified. AVR is characterized by protein...

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Identifiers

PMID: 12199866
DOI: 10.1034/j.1399-3089.2002.01094.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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