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Immunobiology of liver xenotransplantation

1 Sept 2012

Abstract excerpt

Pigs are currently the preferred species for future organ xenotransplantation. With advances in the development of genetically modified pigs, clinical xenotransplantation is becoming closer to reality. In preclinical studies (pig-to-nonhuman primate), the xenotransplantation of livers from pigs transgenic for human CD55 or from α1,3-galactosyltransferase gene-knockout pigs+/- transgenic for human CD46, is...

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PMID: 23078060
DOI: 10.1586/eci.12.56

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